Gene Name	BABAM2
Gene ID	9577
Gene Full Name	BRISC and BRCA1 A complex member 2
Gene Alias	BRCC4|BRCC45|BRE
Transcripts	ENSG00000158019
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Cytosol;
Membrane Info	Metabolic proteins, Predicted intracellular proteins
Uniport_ID	Q9NXR7
HGNC ID	HGNC:1106
OMIM ID	610497
Summary	This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer. [provided by RefSeq, Jun 2016]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6001270	chr2	166	195	146	507	View
6016720	chr2	1	8	3	12	View

Data ID	Experiment type	Sample number	Platform
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - BABAM2 peak across samples

Peak Plot