HBV Target gene Detail Information

> C1R Gene Search Result


Gene Information
Gene Name C1R
Gene ID 715
Gene Full Name complement C1r
Gene Alias EDS8|EDSPD1
Transcripts ENSG00000159403
Virus HBV
Gene Type protein-coding
HPA Location Info Nucleoplasm, Cytosol;
Membrane Info Human disease related genes, Predicted intracellular proteins
HGNC ID HGNC:1246
OMIM ID 613785
Summary This gene encodes a member of the peptidase S1 protein family. The encoded protein is a proteolytic subunit in the complement system C1 complex. The complement system acts as a mediator in the innate immune response by ultimately triggering phagocytosis, inflammation, and rupturing the bacterial cell wall. Mutations in this gene are associated with Ehlers-Danlos Syndrome. [provided by RefSeq, Dec 2018]
Target gene [C1R] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1002187 chr12 306 3 11 320 View
1039106 chr12 251 21 2 274 View
1039107 chr12 238 21 2 261 View
1039108 chr12 238 21 2 261 View
1039109 chr12 226 21 2 249 View
1039110 chr12 220 21 2 243 View
1039111 chr12 206 21 2 229 View
1039112 chr12 205 21 2 228 View

Target gene [C1R] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
S
  GSE199850 		scRNA-seq 1 HiSeq X Ten (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
 
C
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
E
  GSE94660 		RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - C1R expression across samples

Volcano Plot

Bar Plot

> Dataset: GSE94660 - C1R expression across samples

Volcano Plot

Bar Plot