HBV Target gene Detail Information

> C3 Gene Search Result


Gene Information
Gene Name C3
Gene ID 718
Gene Full Name complement C3
Gene Alias AHUS5|ARMD9|ASP|C3a|C3b|CPAMD1|HEL-S-62p
Transcripts ENSG00000125730
Virus HBV
Gene Type protein-coding
HPA Location Info Secreted to blood;
Membrane Info Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P01024
HGNC ID HGNC:1318
OMIM ID 120700
Summary Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]
Target gene [C3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001124 chr19 515 334 195 1044 View
1001125 chr19 515 334 195 1044 View
1001250 chr19 362 309 195 866 View
1002435 chr19 154 77 45 276 View
1002529 chr19 213 34 7 254 View
1003419 chr19 58 37 40 135 View
1004764 chr19 64 3 2 69 View
1007777 chr19 24 0 0 24 View
1007778 chr19 24 0 0 24 View
1008010 chr19 16 6 1 23 View
1013826 chr19 2 2 0 4 View
1024550 chr19 2 2 0 4 View
1039594 chr19 663 408 160 1231 View
1042344 chr19 0 2 0 2 View

Target gene [C3] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
GSE100400 Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE35465 - C3 peak across samples

Peak Plot

> Dataset: GSE68402 - C3 peak across samples

Peak Plot

> Dataset: GSE270130 - C3 peak across samples

Peak Plot

> Dataset: GSE131257 - C3 peak across samples

Peak Plot