HTLV1 Target gene Detail Information

> CBFA2T3 Gene Search Result


Gene Information
Gene Name CBFA2T3
Gene ID 863
Gene Full Name CBFA2/RUNX1 partner transcriptional co-repressor 3
Gene Alias ETO2|MTG16|MTGR2|RUNX1T3|ZMYND4
Transcripts ENSG00000129993
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Cancer-related genes, Disease related genes, Predicted intracellular proteins
Uniport_ID O75081
HGNC ID HGNC:1537
OMIM ID 603870
Summary This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
Target gene [CBFA2T3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6006620 chr16 63 2 0 65 View

Target gene [CBFA2T3] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - CBFA2T3 peak across samples

Peak Plot