XMRV Target gene Detail Information

> CBX1 Gene Search Result


Gene Information
Gene Name CBX1
Gene ID 10951
Gene Full Name chromobox 1
Gene Alias CBX|HP1-BETA|HP1Hs-beta|HP1Hsbeta|Hp1beta|M31|MOD1|p25beta
Transcripts ENSG00000108468
Virus XMRV
Gene Type protein-coding
HPA Location Info Nucleoplasm, Nuclear bodies;
Membrane Info Predicted intracellular proteins
Uniport_ID P83916
HGNC ID HGNC:1551
OMIM ID 604511
Summary This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Target gene [CBX1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
8000061 chr17 3692 3220 1859 8771 View