Gene Name	CCL3
Gene ID	6348
Gene Full Name	C-C motif chemokine ligand 3
Gene Alias	G0S19-1|LD78|LD78ALPHA|MIP-1-alpha|MIP1A|SCI|SCYA3
Transcripts	ENSG00000277632
Virus	EBOV
Gene Type	protein-coding
HPA Location Info	Secreted to blood;
Membrane Info	Cancer-related genes, Predicted secreted proteins
Uniport_ID	P10147
HGNC ID	HGNC:10627
OMIM ID	182283
Summary	This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	31717793	S246P	GP	GP	Cell line	I T	View
2	31717793	S65P	GP	GP	Cell line	I T	View
3	31717793	F934L	L	L	Cell line	I T	View
4	31717793	I1532V	L	L	Cell line	I T	View
5	31717793	C2357A	NP	NP	Cell line	I T	View
6	31717793	H630N	NP	NP	Cell line	I T	View
7	31717793	S72G	NP	NP	Cell line	I T	View
8	31717793	A10979T	VP24	VP24	Cell line	I T	View
9	31717793	K212M	VP24	VP24	Cell line	I T	View
10	31717793	T50I	VP24	VP24	Cell line	I T	View

Data ID	Experiment type	Sample number	Platform
GSE96590	RNA-seq	20	Illumina HiSeq 1000 (Homo sapiens)
GSE80131	RNA-seq	6	Illumina HiSeq 2500 (Homo sapiens)