HTLV1 Target gene Detail Information

> CCR8 Gene Search Result


Gene Information
Gene Name CCR8
Gene ID 1237
Gene Full Name C-C motif chemokine receptor 8
Gene Alias CC-CKR-8|CCR-8|CDw198|CKRL1|CMKBR8|CMKBRL2|CY6|GPRCY6|TER1
Transcripts ENSG00000179934
Virus HTLV1
Gene Type protein-coding
HPA Location Info
Membrane Info CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID P51685
HGNC ID HGNC:1609
OMIM ID 601834
Summary This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]
Target gene [CCR8] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6014327 chr3 11 2 4 17 View

Target gene [CCR8] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
M
  GSE136189 		Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE94732 - CCR8 peak across samples

Peak Plot