Gene Information
|
Gene Name
|
CD63 |
|
Gene ID
|
967
|
|
Gene Full Name
|
CD63 molecule |
|
Gene Alias
|
AD1|HOP-26|ME491|MLA1|OMA81H|Pltgp40|TSPAN30 |
|
Transcripts
|
ENSG00000135404
|
|
Virus
|
HEV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Vesicles;Intracellular and membrane;
|
|
Membrane Info
|
CD markers, Plasma proteins, Predicted membrane proteins, Transporters |
|
Uniport_ID
|
P08962
|
|
HGNC ID
|
HGNC:1692
|
|
OMIM ID
|
155740 |
|
Summary
|
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Apr 2012] |
Target gene [CD63] related to virus gene/protein/region
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [CD63] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE262469
|
RNA-seq |
15 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE251924
|
RNA-seq |
6 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE274780
|
RNA-seq |
12 |
Illumina NextSeq 500 (Homo sapiens) |
|
|