Gene Information
|
Gene Name
|
CDKN2B-AS1 |
|
Gene ID
|
100048912
|
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Gene Full Name
|
CDKN2B and CDKN2A antisense cis and trans regulatory RNA 1 |
|
Gene Alias
|
ANRIL|CDKN2B-AS|CDKN2BAS|NCRNA00089|PCAT12|p15AS |
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Transcripts
|
ENSG00000240498
|
|
Virus
|
HBV |
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Gene Type
|
ncRNA |
|
HGNC ID
|
HGNC:34341
|
|
OMIM ID
|
613149 |
|
lncRNASNP2 ID
|
CDKN2B-AS1
|
|
Summary
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This gene is located within the CDKN2B-CDKN2A gene cluster at chromosome 9p21. The gene product is a functional RNA molecule that interacts with polycomb repressive complex-1 (PRC1) and -2 (PRC2), leading to epigenetic silencing of other genes in this cluster. This region is a significant genetic susceptibility locus for cardiovascular disease, and has also been linked to a number of other pathologies, including several cancers, intracranial aneurysm, type-2 diabetes, periodontitis, Alzheimer's disease, endometriosis, frailty in the elderly, and glaucoma. Multiple alternatively processed transcript variants have been detected, some of which may take the form of circular RNA molecules (PMID:21151960). [provided by RefSeq, May 2014] |
Target gene [CDKN2B-AS1] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1014130 |
chr9 |
3 |
1 |
0 |
4 |
View |
Target gene [CDKN2B-AS1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE236281
|
RNA-seq |
12 |
Illumina MiSeq (Homo sapiens) |
|
C GSE35465
|
Chip-seq;RNA-seq |
6 |
Illumina HiSeq 2000 (Homo sapiens) |
|
C GSE68402
|
Chip-seq |
26 |
Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
|
TCGA_LIHC_HBV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
C GSE270130
|
Chip-seq |
27 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE224901
|
RNA-seq |
21 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE100400
|
Chip-seq;RNA-seq;4C_cccDNA |
31 |
Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus) |
|
GSE173897
|
RNA-seq |
95 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE262515
|
RNA-seq |
21 |
Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus) |
|
GSE110345
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE131257
|
ATAC-seq;RNA-seq |
19 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE94660
|
RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE35465 - CDKN2B-AS1 peak across samples
|
Peak Plot
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> Dataset: GSE68402 - CDKN2B-AS1 peak across samples
|
Peak Plot
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> Dataset: GSE270130 - CDKN2B-AS1 peak across samples
|
Peak Plot
|
> Dataset: GSE100400 - CDKN2B-AS1 peak across samples
|
Peak Plot
|
> Dataset: GSE131257 - CDKN2B-AS1 peak across samples
|
Peak Plot
|
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