Gene Information
|
Gene Name
|
CEP43 |
|
Gene ID
|
11116
|
|
Gene Full Name
|
centrosomal protein 43 |
|
Gene Alias
|
FGFR1OP|FOP |
|
Transcripts
|
ENSG00000213066
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Centrosome, Basal body;Centriolar satellite; 
|
|
Membrane Info
|
Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
O95684
|
|
HGNC ID
|
HGNC:17012
|
|
OMIM ID
|
605392 |
|
Summary
|
This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013] |
Target gene [CEP43] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6017898 |
chr6 |
8 |
2 |
0 |
10 |
View |
| 6027317 |
chr6 |
0 |
2 |
0 |
2 |
View |
Target gene [CEP43] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE52244
|
Expression array |
15 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version] |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - CEP43 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
