Gene Information
|
Gene Name
|
CILK1 |
|
Gene ID
|
22858
|
|
Gene Full Name
|
ciliogenesis associated kinase 1 |
|
Gene Alias
|
ECO|EJM10|ICK|LCK2|MRK|hICK |
|
Transcripts
|
ENSG00000112144
|
|
Virus
|
HPV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Golgi apparatus, Vesicles;Primary cilium, Primary cilium tip; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins |
|
Uniport_ID
|
Q9UPZ9
|
|
HGNC ID
|
HGNC:21219
|
|
OMIM ID
|
612325 |
|
Summary
|
Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008] |
Target gene [CILK1] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 5016134 |
chr6 |
17 |
6 |
0 |
23 |
View |
Target gene [CILK1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE140662
|
Expression array |
8 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
C GSE143026
|
ATAC-seq;Chip-seq;RNA-seq |
30 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE181805
|
Expression array |
25 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE143026 - CILK1 peak across samples
|
Peak Plot
|
|
|
HPV Target gene Detail Information
