HBV Target gene Detail Information

> COL4A6 Gene Search Result


Gene Information
Gene Name COL4A6
Gene ID 1288
Gene Full Name collagen type IV alpha 6 chain
Gene Alias CXDELq22.3|DELXq22.3|DFNX6
Transcripts ENSG00000197565
Virus HBV
Gene Type protein-coding
HPA Location Info Endoplasmic reticulum;Secreted to extracellular matrix;
Membrane Info Disease related genes, Human disease related genes, Predicted secreted proteins
Uniport_ID Q14031
HGNC ID HGNC:2208
OMIM ID 303631
Summary This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Target gene [COL4A6] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1015937 chrX 2 0 0 2 View
1016704 chrX 0 1 0 1 View
1016705 chrX 0 1 0 1 View
1024473 chrX 1 1 0 2 View

Target gene [COL4A6] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
GSE199850 scRNA-seq 1 HiSeq X Ten (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
GSE100400 Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE35465 - COL4A6 peak across samples

Peak Plot

> Dataset: GSE68402 - COL4A6 peak across samples

Peak Plot

> Dataset: GSE270130 - COL4A6 peak across samples

Peak Plot

> Dataset: GSE131257 - COL4A6 peak across samples

Peak Plot