HBV Target gene Detail Information

> CPS1 Gene Search Result


Gene Information
Gene Name CPS1
Gene ID 1373
Gene Full Name carbamoyl-phosphate synthase 1
Gene Alias CPSASE1|GATD6|PHN
Transcripts ENSG00000021826
Virus HBV
Gene Type protein-coding
HPA Location Info Nucleoli, Nucleoli rim;Mid piece, Principal piece;
Membrane Info Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins
Uniport_ID P31327
HGNC ID HGNC:2323
OMIM ID 608307
Summary The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.[provided by RefSeq, May 2010]
Target gene [CPS1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001896 chr2 196 115 118 429 View
1001916 chr2 196 113 113 422 View
1004065 chr2 22 72 1 95 View
1004469 chr2 7 60 13 80 View
1004876 chr2 9 37 21 67 View
1005652 chr2 8 42 0 50 View
1006951 chr2 18 11 3 32 View
1008082 chr2 21 1 0 22 View
1009535 chr2 2 7 6 15 View
1009669 chr2 15 0 0 15 View
1010487 chr2 4 3 5 12 View
1010531 chr2 8 4 0 12 View
1010550 chr2 8 4 0 12 View
1010602 chr2 6 4 1 11 View
1011700 chr2 0 6 2 8 View
1011953 chr2 4 4 0 8 View
1014591 chr2 2 1 0 3 View
1015418 chr2 2 0 0 2 View
1015467 chr2 1 1 0 2 View
1015468 chr2 1 1 0 2 View
1016090 chr2 0 2 0 2 View
1016190 chr2 1 0 0 1 View
1016830 chr2 1 0 0 1 View
1016897 chr2 0 1 0 1 View
1018844 chr2 0 0 0 0 View
1019280 chr2 0 0 0 0 View
1019281 chr2 0 0 0 0 View
1019742 chr2 0 0 0 0 View
1019831 chr2 0 0 0 0 View
1019878 chr2 0 0 0 0 View
1019891 chr2 0 0 0 0 View
1019955 chr2 0 0 0 0 View
1021199 chr2 21 1 0 22 View
1021909 chr2 6 4 1 11 View
1024301 chr2 15 14 4 33 View
1041292 chr2 0 0 1 1 View
1041293 chr2 28 24 0 52 View
1041294 chr2 22 20 0 42 View
1042561 chr2 59 2 0 61 View
1042562 chr2 27 2 0 29 View
1042563 chr2 28 2 0 30 View
1042564 chr2 0 1 0 1 View
1042565 chr2 14 6 3 23 View
1042566 chr2 14 5 3 22 View

Target gene [CPS1] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
E
  GSE94660 		RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE94660 - CPS1 expression across samples

Volcano Plot

Bar Plot