Gene Name	CSF3
Gene ID	1440
Gene Full Name	colony stimulating factor 3
Gene Alias	C17orf33|CSF3OS|GCSF
Transcripts	ENSG00000108342
Virus	EBOV
Gene Type	protein-coding
HPA Location Info	Secreted to blood;
Membrane Info	Cancer-related genes, Plasma proteins, Predicted secreted proteins
Uniport_ID	P09919
HGNC ID	HGNC:2438
OMIM ID	138970
Summary	This gene encodes a member of the IL-6 superfamily of cytokines. The encoded cytokine controls the production, differentiation, and function of granulocytes. Granulocytes are a type of white blood cell that are part of the innate immune response. A modified form of this protein is commonly administered to manage chemotherapy-induced neutropenia. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2020]

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	31717793	S246P	GP	GP	Cell line	I T	View
2	31717793	S65P	GP	GP	Cell line	I T	View
3	31717793	F934L	L	L	Cell line	I T	View
4	31717793	I1532V	L	L	Cell line	I T	View
5	31717793	C2357A	NP	NP	Cell line	I T	View
6	31717793	H630N	NP	NP	Cell line	I T	View
7	31717793	S72G	NP	NP	Cell line	I T	View
8	31717793	A10979T	VP24	VP24	Cell line	I T	View
9	31717793	K212M	VP24	VP24	Cell line	I T	View
10	31717793	T50I	VP24	VP24	Cell line	I T	View

Data ID	Experiment type	Sample number	Platform
GSE96590	RNA-seq	20	Illumina HiSeq 1000 (Homo sapiens)
GSE80131	RNA-seq	6	Illumina HiSeq 2500 (Homo sapiens)