Gene Information
|
Gene Name
|
CXCL10 |
|
Gene ID
|
3627
|
|
Gene Full Name
|
C-X-C motif chemokine ligand 10 |
|
Gene Alias
|
C7|IFI10|INP10|IP-10|SCYB10|crg-2|gIP-10|mob-1 |
|
Transcripts
|
ENSG00000169245
|
|
Virus
|
EBOV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Secreted to blood; 
|
|
Membrane Info
|
Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins |
|
Uniport_ID
|
P02778
|
|
HGNC ID
|
HGNC:10637
|
|
OMIM ID
|
147310 |
|
Summary
|
This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection. [provided by RefSeq, Sep 2020] |
Target gene [CXCL10] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [CXCL10] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
E GSE96590
|
RNA-seq |
20 |
Illumina HiSeq 1000 (Homo sapiens) |
|
GSE80131
|
RNA-seq |
6 |
Illumina HiSeq 2500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE96590 - CXCL10 expression across samples
|
Volcano Plot
|
Bar Plot
|
|
|
EBOV Target gene Detail Information
