Gene Name	CYP3A7-CYP3A51P
Gene ID	100861540
Gene Full Name	CYP3A7-CYP3A51P readthrough
Gene Alias	CYP3A7|CYP3A7-3AP1|CYP3A7-CYP3AP1|CYP3A7.1L|CYPIIIA7
Transcripts	ENSG00000282301
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Cytosol;Vesicles;
Membrane Info	Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins
HGNC ID	HGNC:51504
Summary	This locus represents readthrough transcription between the neighboring CYP3A7 (cytochrome P450, family 3, subfamily A, polypeptide 7) and CYP3A51P (cytochrome P450, family 3, subfamily A, polypeptide 51, pseudogene) genes, which are members of the CYP3A gene cluster on chromosome 7. The downstream pseudogene is not known to be independently transcribed. The readthrough transcript includes CYP3A7 exons 1-13 and exons 2 and 13 of the pseudogene. It encodes a CYP3A isoform with a novel C-terminus. This isoform is only expressed in alleles containing a T nucleotide at the -6 position of a splice acceptor in the pseudogene, which enables correct splicing of the upstream CYP3A7 exons to the pseudogene exons. It should be noted that the reference genome sequence represents the CYP3A7_39256 T->A allele, and thus this haplotype is unlikely to produce the readthrough transcript. [provided by RefSeq, Jan 2015]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6008915	chr7	29	11	1	41	View

Data ID	Experiment type	Sample number	Platform
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - CYP3A7-CYP3A51P peak across samples

Peak Plot