HBV Target gene Detail Information

> DARS1 Gene Search Result


Gene Information
Gene Name DARS1
Gene ID 1615
Gene Full Name aspartyl-tRNA synthetase 1
Gene Alias DARS|HBSL|aspRS
Transcripts ENSG00000115866
Virus HBV
Gene Type protein-coding
HPA Location Info Cytosol;
Membrane Info Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID P14868
HGNC ID HGNC:2678
OMIM ID 603084
Summary This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Target gene [DARS1] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1042533 chr2 21 4 0 25 View

Target gene [DARS1] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
GSE100400 Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE35465 - DARS1 peak across samples

Peak Plot

> Dataset: GSE68402 - DARS1 peak across samples

Peak Plot

> Dataset: GSE270130 - DARS1 peak across samples

Peak Plot

> Dataset: GSE131257 - DARS1 peak across samples

Peak Plot