Gene Name	DCAF1
Gene ID	9730
Gene Full Name	DDB1 and CUL4 associated factor 1
Gene Alias	RIP|VPRBP
Transcripts	ENSG00000145041
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;Nucleoli fibrillar center;
Membrane Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9Y4B6
HGNC ID	HGNC:30911
OMIM ID	617259
Summary	Enables histone H2AT120 kinase activity; nuclear estrogen receptor binding activity; and ubiquitin-like ligase-substrate adaptor activity. Involved in several processes, including cell competition in a multicellular organism; proteasome-mediated ubiquitin-dependent protein catabolic process; and regulation of primary metabolic process. Located in COP9 signalosome; fibrillar center; and nucleoplasm. Part of Cul4-RING E3 ubiquitin ligase complex. Is active in centrosome. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6022602	chr3	3	2	0	5	View

Data ID	Experiment type	Sample number	Platform
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - DCAF1 peak across samples

Peak Plot