HBV Target gene Detail Information

> DOK5 Gene Search Result


Gene Information
Gene Name DOK5
Gene ID 55816
Gene Full Name docking protein 5
Gene Alias C20orf180|IRS-6|IRS6
Transcripts ENSG00000101134
Virus HBV
Gene Type protein-coding
HPA Location Info Focal adhesion sites;
Membrane Info Predicted intracellular proteins
Uniport_ID Q9P104
HGNC ID HGNC:16173
OMIM ID 608334
Summary The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Target gene [DOK5] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005830 chr20 34 12 1 47 View
1005872 chr20 33 12 1 46 View
1005873 chr20 33 12 1 46 View
1005874 chr20 33 12 1 46 View
1005875 chr20 33 12 1 46 View
1005876 chr20 33 12 1 46 View
1005897 chr20 33 12 1 46 View
1005917 chr20 33 12 1 46 View
1009941 chr20 2 6 6 14 View

Target gene [DOK5] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
GSE100400 Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE68402 - DOK5 peak across samples

Peak Plot

> Dataset: GSE270130 - DOK5 peak across samples

Peak Plot

> Dataset: GSE131257 - DOK5 peak across samples

Peak Plot