Gene Name	ERBIN
Gene ID	55914
Gene Full Name	erbb2 interacting protein
Gene Alias	ERBB2IP|HEL-S-78|LAP2
Transcripts	ENSG00000112851
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Plasma membrane, Cell Junctions;
Membrane Info	Predicted intracellular proteins
Uniport_ID	Q96RT1
HGNC ID	HGNC:15842
OMIM ID	606944
Summary	This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6006708	chr5	22	36	6	64	View
6028469	chr5	1	0	0	1	View

Data ID	Experiment type	Sample number	Platform
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - ERBIN peak across samples

Peak Plot