Gene Information
|
Gene Name
|
EXOC6B |
|
Gene ID
|
23233
|
|
Gene Full Name
|
exocyst complex component 6B |
|
Gene Alias
|
SEC15B|SEC15L2|SEMDJL3 |
|
Transcripts
|
ENSG00000144036
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm, Nuclear bodies;Cytosol;
|
|
Membrane Info
|
Disease related genes, Human disease related genes, Predicted intracellular proteins |
|
Uniport_ID
|
Q9Y2D4
|
|
HGNC ID
|
HGNC:17085
|
|
OMIM ID
|
607880 |
|
Summary
|
This gene encodes a protein which is a part of the evolutionarily conserved exocyst, a multimeric protein complex necessary for exocytosis, which in turn, is crucial for cell growth, polarity and migration. Disruption of this gene may be associated with phenotypes exhibiting multiple symptoms including intellectual disability and developmental delay (DD). [provided by RefSeq, Jun 2016] |
Target gene [EXOC6B] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6012305 |
chr2 |
12 |
3 |
8 |
23 |
View |
| 6014896 |
chr2 |
13 |
2 |
0 |
15 |
View |
| 6015192 |
chr2 |
0 |
12 |
3 |
15 |
View |
| 6019197 |
chr2 |
4 |
2 |
2 |
8 |
View |
| 6024797 |
chr2 |
0 |
1 |
2 |
3 |
View |
| 6028457 |
chr2 |
0 |
1 |
0 |
1 |
View |
| 6029508 |
chr2 |
1 |
0 |
0 |
1 |
View |
| 6030342 |
chr2 |
1 |
0 |
0 |
1 |
View |
Target gene [EXOC6B] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - EXOC6B peak across samples
|
Peak Plot
|
|
|