Gene Name	EYS
Gene ID	346007
Gene Full Name	eyes shut homolog
Gene Alias	C6orf178|C6orf179|C6orf180|EGFL10|EGFL11|RP25|SPAM|bA166P24.2|bA307F22.3|bA74E24.1|dJ1018A4.2|dJ22I17.2|dJ303F19.1
Transcripts	ENSG00000188107
Virus	HBV
Gene Type	protein-coding
HPA Location Info	Plasma membrane, Cytosol, Flagellar centriole;Secreted in other tissues;
Membrane Info	Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	Q5T1H1
HGNC ID	HGNC:21555
OMIM ID	612424
Summary	The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains. The protein is expressed in the photoreceptor layer of the retina, and the gene is mutated in autosomal recessive retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005171	chr6	4	21	34	59	View
1005621	chr6	4	19	27	50	View
1006965	chr6	29	2	2	33	View
1007680	chr6	14	11	0	25	View
1011555	chr6	9	0	0	9	View
1011892	chr6	4	4	0	8	View
1012413	chr6	5	0	2	7	View
1014333	chr6	3	0	0	3	View
1014898	chr6	2	0	1	3	View
1016437	chr6	0	1	0	1	View
1018859	chr6	0	0	0	0	View
1019149	chr6	0	0	0	0	View
1019202	chr6	0	0	0	0	View
1019219	chr6	0	0	0	0	View
1019337	chr6	0	0	0	0	View
1024075	chr6	0	0	0	0	View
1041481	chr6	0	1	0	1	View

Data ID	Experiment type	Sample number	Platform
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
C   GSE35465	Chip-seq;RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
C   GSE68402	Chip-seq	26	Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
C   GSE270130	Chip-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
C   GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE35465 - EYS peak across samples

Peak Plot

> Dataset: GSE68402 - EYS peak across samples

Peak Plot

> Dataset: GSE270130 - EYS peak across samples

Peak Plot

> Dataset: GSE100400 - EYS peak across samples

Peak Plot

> Dataset: GSE131257 - EYS peak across samples

Peak Plot