Gene Information
|
Gene Name
|
GABRB3 |
|
Gene ID
|
2562
|
|
Gene Full Name
|
gamma-aminobutyric acid type A receptor subunit beta3 |
|
Gene Alias
|
DEE43|ECA5|EIEE43 |
|
Transcripts
|
ENSG00000166206
|
|
Virus
|
HBV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
|
|
Membrane Info
|
Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters |
|
Uniport_ID
|
P28472
|
|
HGNC ID
|
HGNC:4083
|
|
OMIM ID
|
137192 |
|
Summary
|
This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one the subunits of a multi-subunit chloride channel that serves as the receptor for gamma-aminobutyric acid, a major inhibitory neurotransmitter of the mammalian nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two other genes encoding related subunits of the family. This gene may be associated with the pathogenesis of several disorders including Angelman syndrome, Prader-Willi syndrome, nonsyndromic orofacial clefts, epilepsy and autism. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2013] |
Target gene [GABRB3] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1003433 |
chr15 |
0 |
132 |
2 |
134 |
View |
| 1003511 |
chr15 |
48 |
23 |
57 |
128 |
View |
| 1010211 |
chr15 |
0 |
12 |
1 |
13 |
View |
| 1041125 |
chr15 |
0 |
0 |
0 |
0 |
View |
Target gene [GABRB3] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE236281
|
RNA-seq |
12 |
Illumina MiSeq (Homo sapiens) |
|
C GSE68402
|
Chip-seq |
26 |
Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
|
TCGA_LIHC_HBV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
C GSE270130
|
Chip-seq |
27 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE224901
|
RNA-seq |
21 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
C GSE100400
|
Chip-seq;RNA-seq;4C_cccDNA |
31 |
Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus) |
|
GSE173897
|
RNA-seq |
95 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE262515
|
RNA-seq |
21 |
Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus) |
|
GSE110345
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE131257
|
ATAC-seq;RNA-seq |
19 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE94660
|
RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE68402 - GABRB3 peak across samples
|
Peak Plot
|
> Dataset: GSE270130 - GABRB3 peak across samples
|
Peak Plot
|
> Dataset: GSE100400 - GABRB3 peak across samples
|
Peak Plot
|
> Dataset: GSE131257 - GABRB3 peak across samples
|
Peak Plot
|
|
|
HBV Target gene Detail Information
