HBV Target gene Detail Information

> GLI2 Gene Search Result


Gene Information
Gene Name GLI2
Gene ID 2736
Gene Full Name GLI family zinc finger 2
Gene Alias CJS|HPE9|PHS2|THP1|THP2
Transcripts ENSG00000074047
Virus HBV
Gene Type protein-coding
HPA Location Info Nucleoplasm, Nucleoli;Centrosome, Basal body;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID P10070
HGNC ID HGNC:4318
OMIM ID 165230
Summary This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]
Target gene [GLI2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000303 chr2 2786 2556 1139 6481 View
1000304 chr2 2786 2556 1139 6481 View
1000305 chr2 2786 2556 1139 6481 View
1000306 chr2 2786 2556 1139 6481 View
1000307 chr2 2786 2556 1139 6481 View
1000308 chr2 2786 2556 1139 6481 View
1002256 chr2 34 46 226 306 View
1002594 chr2 80 105 67 252 View
1003895 chr2 20 45 38 103 View
1004012 chr2 78 15 6 99 View
1004467 chr2 19 7 54 80 View
1004724 chr2 67 3 0 70 View
1005655 chr2 35 8 7 50 View
1005656 chr2 35 8 7 50 View
1006548 chr2 15 18 4 37 View
1006549 chr2 15 18 4 37 View
1006618 chr2 28 8 0 36 View
1006640 chr2 21 9 6 36 View
1007167 chr2 22 8 0 30 View
1007251 chr2 27 2 0 29 View
1007871 chr2 15 3 6 24 View
1008444 chr2 11 10 0 21 View
1010212 chr2 9 4 0 13 View
1010799 chr2 9 2 0 11 View
1012008 chr2 8 0 0 8 View
1012891 chr2 5 1 0 6 View
1012892 chr2 5 1 0 6 View
1042524 chr2 18 4 1 23 View

Target gene [GLI2] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - GLI2 expression across samples

Volcano Plot

Bar Plot