HTLV1 Target gene Detail Information

> GRK3 Gene Search Result


Gene Information
Gene Name GRK3
Gene ID 157
Gene Full Name G protein-coupled receptor kinase 3
Gene Alias ADRBK2|BARK2
Transcripts ENSG00000100077
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm;Plasma membrane;
Membrane Info Enzymes, Metabolic proteins, Predicted intracellular proteins
Uniport_ID P35626
HGNC ID HGNC:290
OMIM ID 109636
Summary The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008]
Target gene [GRK3] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6005099 chr22 66 25 5 96 View
6011156 chr22 12 2 13 27 View
6011251 chr22 22 5 0 27 View

Target gene [GRK3] related to Omics data
Data ID Experiment type Sample number Platform
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE10789 Expression array 6 NCI/ATC Hs-OperonV3
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
C
  GSE94732
Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - GRK3 peak across samples

Peak Plot