Gene Name	GSDME
Gene ID	1687
Gene Full Name	gasdermin E
Gene Alias	DFNA5|ICERE-1
Transcripts	ENSG00000105928
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Cytosol;
Membrane Info	Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	O60443
HGNC ID	HGNC:2810
OMIM ID	608798
Summary	Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6002606	chr7	24	101	100	225	View
6024247	chr7	1	2	0	3	View

Data ID	Experiment type	Sample number	Platform
GSE52244	Expression array	15	[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - GSDME peak across samples

Peak Plot