Gene Name	HMGB1
Gene ID	3146
Gene Full Name	high mobility group box 1
Gene Alias	HMG-1|HMG1|HMG3|SBP-1
Transcripts	ENSG00000189403
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;Secreted to blood;
Membrane Info	Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	P09429
HGNC ID	HGNC:4983
OMIM ID	163905
Summary	This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6007877	chr13	51	0	0	51	View
6025076	chr13	2	0	1	3	View
6031424	chr13	0	0	0	0	View

Data ID	Experiment type	Sample number	Platform
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
GSE10789	Expression array	6	NCI/ATC Hs-OperonV3
GSE224047	RNA-seq	10	Illumina NextSeq 500 (Homo sapiens)
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
GSE136189	Methylation profiling (Array)	40	Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - HMGB1 peak across samples

Peak Plot