Gene Information
|
Gene Name
|
IFIT1 |
|
Gene ID
|
3434
|
|
Gene Full Name
|
interferon induced protein with tetratricopeptide repeats 1 |
|
Gene Alias
|
C56|G10P1|IFI-56|IFI-56K|IFI56|IFIT-1|IFNAI1|ISG56|P56|RNM561 |
|
Transcripts
|
ENSG00000185745
|
|
Virus
|
EBOV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cytosol;
|
|
Membrane Info
|
Predicted intracellular proteins |
|
Uniport_ID
|
P09914
|
|
HGNC ID
|
HGNC:5407
|
|
OMIM ID
|
147690 |
|
Summary
|
This gene encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. The encoded protein may inhibit viral replication and translational initiation. This gene is located in a cluster on chromosome 10 with five other closely related genes. There is a pseudogene for this gene on chromosome 13. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012] |
Target gene [IFIT1] related to virus gene/protein/region
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
| ID |
PMID |
Mutation |
Gene/Protein/Region |
Encoding Gene/Protein |
Disease |
Description |
Detail |
| 1 |
18353943 |
R312A |
VP35
|
VP35
|
Cell line
|
G
I
T
|
View |
Target gene [IFIT1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE96590
|
RNA-seq |
20 |
Illumina HiSeq 1000 (Homo sapiens) |
|
GSE80131
|
RNA-seq |
6 |
Illumina HiSeq 2500 (Homo sapiens) |