Gene Information
|
Gene Name
|
IFIT3 |
|
Gene ID
|
3437
|
|
Gene Full Name
|
interferon induced protein with tetratricopeptide repeats 3 |
|
Gene Alias
|
CIG-49|GARG-49|IFI60|IFIT4|IRG2|ISG60|P60|RIG-G|cig41 |
|
Transcripts
|
ENSG00000119917
|
|
Virus
|
EBOV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Mitochondria, Cytosol;
|
|
Membrane Info
|
Plasma proteins, Predicted intracellular proteins |
|
Uniport_ID
|
O14879
|
|
HGNC ID
|
HGNC:5411
|
|
OMIM ID
|
604650 |
|
Summary
|
Enables identical protein binding activity. Involved in antiviral innate immune response; negative regulation of apoptotic process; and negative regulation of cell population proliferation. Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Apr 2025] |
Target gene [IFIT3] related to virus gene/protein/region
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
| ID |
PMID |
Mutation |
Gene/Protein/Region |
Encoding Gene/Protein |
Disease |
Description |
Detail |
| 1 |
18353943 |
R312A |
VP35
|
VP35
|
Cell line
|
G
I
T
|
View |
Target gene [IFIT3] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE96590
|
RNA-seq |
20 |
Illumina HiSeq 1000 (Homo sapiens) |
|
GSE80131
|
RNA-seq |
6 |
Illumina HiSeq 2500 (Homo sapiens) |
|
|