Gene Information
|
Gene Name
|
IKBKE |
|
Gene ID
|
9641
|
|
Gene Full Name
|
inhibitor of nuclear factor kappa B kinase subunit epsilon |
|
Gene Alias
|
IKK-E|IKK-i|IKKE|IKKI |
|
Transcripts
|
ENSG00000263528
|
|
Virus
|
EBOV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Cytosol; 
|
|
Membrane Info
|
Enzymes, Predicted intracellular proteins |
|
Uniport_ID
|
Q14164
|
|
HGNC ID
|
HGNC:14552
|
|
OMIM ID
|
605048 |
|
Summary
|
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009] |
Target gene [IKBKE] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [IKBKE] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
E GSE96590
|
RNA-seq |
20 |
Illumina HiSeq 1000 (Homo sapiens) |
|
GSE80131
|
RNA-seq |
6 |
Illumina HiSeq 2500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE96590 - IKBKE expression across samples
|
Volcano Plot
|
Bar Plot
|
|
|
EBOV Target gene Detail Information
