Gene Information
|
Gene Name
|
IL15RA |
|
Gene ID
|
3601
|
|
Gene Full Name
|
interleukin 15 receptor subunit alpha |
|
Gene Alias
|
CD215 |
|
Transcripts
|
ENSG00000134470
|
|
Virus
|
EBOV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Vesicles, Plasma membrane;Cytosol;Secreted to blood; 
|
|
Membrane Info
|
CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins |
|
Uniport_ID
|
Q13261
|
|
HGNC ID
|
HGNC:5978
|
|
OMIM ID
|
601070 |
|
Summary
|
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.[provided by RefSeq, Apr 2010] |
Target gene [IL15RA] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [IL15RA] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
E GSE96590
|
RNA-seq |
20 |
Illumina HiSeq 1000 (Homo sapiens) |
|
GSE80131
|
RNA-seq |
6 |
Illumina HiSeq 2500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE96590 - IL15RA expression across samples
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Volcano Plot
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Bar Plot
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|
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EBOV Target gene Detail Information
