Gene Information
|
Gene Name
|
KCNT1 |
|
Gene ID
|
57582
|
|
Gene Full Name
|
potassium sodium-activated channel subfamily T member 1 |
|
Gene Alias
|
DEE14|EIEE14|ENFL5|KCa4.1|KNa1.1|SLACK|Slo2.2|bA100C15.2 |
|
Transcripts
|
ENSG00000107147
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane;Nucleoplasm; 
|
|
Membrane Info
|
Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels |
|
Uniport_ID
|
Q5JUK3
|
|
HGNC ID
|
HGNC:18865
|
|
OMIM ID
|
608167 |
|
Summary
|
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] |
Target gene [KCNT1] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6006951 |
chr9 |
51 |
9 |
1 |
61 |
View |
| 6008335 |
chr9 |
5 |
11 |
30 |
46 |
View |
| 6011587 |
chr9 |
24 |
2 |
0 |
26 |
View |
Target gene [KCNT1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - KCNT1 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
