Gene Information
|
Gene Name
|
KPNA1 |
|
Gene ID
|
3836
|
|
Gene Full Name
|
karyopherin subunit alpha 1 |
|
Gene Alias
|
IPOA5|NPI-1|RCH2|SRP1 |
|
Transcripts
|
ENSG00000114030
|
|
Virus
|
EBOV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;Cytosol; 
|
|
Membrane Info
|
Predicted intracellular proteins, Transporters |
|
Uniport_ID
|
P52294
|
|
HGNC ID
|
HGNC:6394
|
|
OMIM ID
|
600686 |
|
Summary
|
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import. This protein interacts with the recombination activating gene 1 (RAG1) protein and is a putative substrate of the RAG1 ubiquitin ligase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] |
Target gene [KPNA1] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
Target gene [KPNA1] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE96590
|
RNA-seq |
20 |
Illumina HiSeq 1000 (Homo sapiens) |
|
GSE80131
|
RNA-seq |
6 |
Illumina HiSeq 2500 (Homo sapiens) |
|
|
EBOV Target gene Detail Information
