Gene Information
|
Gene Name
|
LAMA5 |
|
Gene ID
|
3911
|
|
Gene Full Name
|
laminin subunit alpha 5 |
|
Gene Alias
|
BBDS2|NPHS26 |
|
Transcripts
|
ENSG00000130702
|
|
Virus
|
HBV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Vesicles;Secreted to extracellular matrix;
|
|
Membrane Info
|
Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
|
Uniport_ID
|
O15230
|
|
HGNC ID
|
HGNC:6485
|
|
OMIM ID
|
601033 |
|
Summary
|
This gene encodes one of the vertebrate laminin alpha chains. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. The protein encoded by this gene is the alpha-5 subunit of of laminin-10 (laminin-511), laminin-11 (laminin-521) and laminin-15 (laminin-523). [provided by RefSeq, Jun 2013] |
Target gene [LAMA5] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1007265 |
chr20 |
27 |
1 |
0 |
28 |
View |
| 1009486 |
chr20 |
15 |
0 |
0 |
15 |
View |
| 1023096 |
chr20 |
27 |
1 |
0 |
28 |
View |
| 1023097 |
chr20 |
15 |
0 |
0 |
15 |
View |
| 1024553 |
chr20 |
37 |
112 |
43 |
192 |
View |
| 1042673 |
chr20 |
30 |
2 |
0 |
32 |
View |
Target gene [LAMA5] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE236281
|
RNA-seq |
12 |
Illumina MiSeq (Homo sapiens) |
|
C GSE35465
|
Chip-seq;RNA-seq |
6 |
Illumina HiSeq 2000 (Homo sapiens) |
|
C GSE68402
|
Chip-seq |
26 |
Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
|
TCGA_LIHC_HBV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
C GSE270130
|
Chip-seq |
27 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE224901
|
RNA-seq |
21 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE100400
|
Chip-seq;RNA-seq;4C_cccDNA |
31 |
Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus) |
|
GSE173897
|
RNA-seq |
95 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE262515
|
RNA-seq |
21 |
Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus) |
|
GSE110345
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE131257
|
ATAC-seq;RNA-seq |
19 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE94660
|
RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE35465 - LAMA5 peak across samples
|
Peak Plot
|
> Dataset: GSE68402 - LAMA5 peak across samples
|
Peak Plot
|
> Dataset: GSE270130 - LAMA5 peak across samples
|
Peak Plot
|
> Dataset: GSE131257 - LAMA5 peak across samples
|
Peak Plot
|
|
|