Gene Information
|
Gene Name
|
MARCHF2 |
|
Gene ID
|
51257
|
|
Gene Full Name
|
membrane associated ring-CH-type finger 2 |
|
Gene Alias
|
HSPC240|MARCH-II|MARCH2|RNF172 |
|
Transcripts
|
ENSG00000099785
|
|
Virus
|
HPV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Endoplasmic reticulum;Cytosol; 
|
|
Membrane Info
|
Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters |
|
Uniport_ID
|
Q9P0N8
|
|
HGNC ID
|
HGNC:28038
|
|
OMIM ID
|
613332 |
|
Summary
|
MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010] |
Target gene [MARCHF2] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 5000285 |
chr19 |
187 |
84 |
91 |
362 |
View |
| 5002732 |
chr1 |
0 |
8 |
0 |
8 |
View |
Target gene [MARCHF2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
TCGA_CESC
|
DNA methylation sequencing;RNA-seq |
288 |
TCGA |
|
GSE140662
|
Expression array |
8 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
|
C GSE143026
|
ATAC-seq;Chip-seq;RNA-seq |
30 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE181805
|
Expression array |
25 |
[HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version] |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE143026 - MARCHF2 peak across samples
|
Peak Plot
|
|
|
HPV Target gene Detail Information
