Gene Name	MIR6730
Gene ID	102466722
Gene Full Name	microRNA 6730
Gene Alias	hsa-mir-6730
Transcripts	ENSG00000276830
Virus	HPV
Gene Type	ncRNA
HGNC ID	HGNC:50222
Summary	microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5005545	chr3	2	1	0	3	View

Data ID	Experiment type	Sample number	Platform
TCGA_CESC	DNA methylation sequencing;RNA-seq	288	TCGA
C   GSE183048	Chip-seq	24	Illumina HiSeq 4000 (Homo sapiens)
C   GSE143026	ATAC-seq;Chip-seq;RNA-seq	30	Illumina HiSeq 2500 (Homo sapiens)
GSE196215	RNA-seq	8	Illumina NovaSeq 6000 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE183048 - MIR6730 peak across samples

Peak Plot

> Dataset: GSE143026 - MIR6730 peak across samples

Peak Plot