HTLV1 Target gene Detail Information

> MRTFA Gene Search Result


Gene Information
Gene Name MRTFA
Gene ID 57591
Gene Full Name myocardin related transcription factor A
Gene Alias BSAC|MAL|MKL|MKL1|MRTF-A
Transcripts ENSG00000196588
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm;Cytosol;
Membrane Info Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID Q969V6
HGNC ID HGNC:14334
OMIM ID 606078
Summary The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Target gene [MRTFA] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6005715 chr22 36 14 32 82 View
6011571 chr22 24 2 0 26 View

Target gene [MRTFA] related to Omics data
Data ID Experiment type Sample number Platform
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
C
  GSE94732
Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - MRTFA peak across samples

Peak Plot