HBV Target gene Detail Information

> MTREX Gene Search Result


Gene Information
Gene Name MTREX
Gene ID 23517
Gene Full Name Mtr4 exosome RNA helicase
Gene Alias Dob1|KIAA0052|Mtr4|SKIV2L2|fSAP118
Transcripts ENSG00000039123
Virus HBV
Gene Type protein-coding
HPA Location Info Nucleoplasm;
Membrane Info Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins
Uniport_ID P42285
HGNC ID HGNC:18734
OMIM ID 618122
Summary Enables ATP binding activity and RNA helicase activity. Involved in DNA damage response; RNA catabolic process; and maturation of 5.8S rRNA. Located in nuclear exosome (RNase complex) and nucleoplasm. Part of TRAMP complex and catalytic step 2 spliceosome. Biomarker of amyotrophic lateral sclerosis. [provided by Alliance of Genome Resources, Apr 2025]
Target gene [MTREX] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004908 chr5 55 9 2 66 View
1006992 chr5 27 2 2 31 View

Target gene [MTREX] related to Omics data
Data ID Experiment type Sample number Platform
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
GSE199850 scRNA-seq 1 HiSeq X Ten (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
GSE100400 Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE35465 - MTREX peak across samples

Peak Plot

> Dataset: GSE68402 - MTREX peak across samples

Peak Plot

> Dataset: GSE270130 - MTREX peak across samples

Peak Plot

> Dataset: GSE131257 - MTREX peak across samples

Peak Plot