HTLV1 Target gene Detail Information

> MTRFR Gene Search Result


Gene Information
Gene Name MTRFR
Gene ID 91574
Gene Full Name mitochondrial translation release factor in rescue
Gene Alias C12orf65|COXPD7|SPG55|mtRF-R
Transcripts ENSG00000130921
Virus HTLV1
Gene Type protein-coding
HPA Location Info Nucleoplasm, Cytosol;Mitochondria;
Membrane Info Disease related genes, Human disease related genes, Predicted intracellular proteins
Uniport_ID Q9H3J6
HGNC ID HGNC:26784
OMIM ID 613541
Summary This nuclear gene encodes a mitochondrial matrix protein that appears to contribute to peptide chain termination in the mitochondrial translation machinery. Two different 1 bp deletions (resulting in the same premature stop codon)result in decreased mitochondrial translation, decreased levels of oxidative phosphorylation complexes and encepthalomyopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Target gene [MTRFR] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000203 chr12 2892 143 25 3060 View

Target gene [MTRFR] related to Omics data
Data ID Experiment type Sample number Platform
GSE52244 Expression array 15 [HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [probe set (exon) version]
GSE224047 RNA-seq 10 Illumina NextSeq 500 (Homo sapiens)
C
  GSE94732 		Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - MTRFR peak across samples

Peak Plot