Gene Name	MX1
Gene ID	4599
Gene Full Name	MX dynamin like GTPase 1
Gene Alias	IFI-78K|IFI78|MX|MxA|lncMX1-215
Transcripts	ENSG00000157601
Virus	EBOV
Gene Type	protein-coding
HPA Location Info	Nuclear membrane, Cytosol;
Membrane Info	Predicted intracellular proteins
Uniport_ID	P20591
HGNC ID	HGNC:7532
OMIM ID	147150
Summary	This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	18353943	R312A	VP35	VP35	Cell line	G I T	View

Data ID	Experiment type	Sample number	Platform
GSE96590	RNA-seq	20	Illumina HiSeq 1000 (Homo sapiens)
GSE80131	RNA-seq	6	Illumina HiSeq 2500 (Homo sapiens)