Gene Name	NRXN3
Gene ID	9369
Gene Full Name	neurexin 3
Gene Alias	C14orf60
Transcripts	ENSG00000021645
Virus	HBV
Gene Type	protein-coding
HPA Location Info
Membrane Info	Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9HDB5, Q9Y4C0
HGNC ID	HGNC:8010
OMIM ID	600567
Summary	This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1009516	chr14	3	5	7	15	View
1013343	chr14	2	2	1	5	View
1013344	chr14	2	2	1	5	View
1014656	chr14	3	0	0	3	View
1015164	chr14	0	2	0	2	View
1016307	chr14	0	0	1	1	View
1016697	chr14	0	1	0	1	View
1016698	chr14	0	1	0	1	View
1016890	chr14	0	1	0	1	View
1016987	chr14	0	1	0	1	View
1017089	chr14	0	1	0	1	View
1017111	chr14	0	1	0	1	View
1022551	chr14	0	0	1	1	View
1024172	chr14	2	2	0	4	View
1042100	chr14	32	6	0	38	View

Data ID	Experiment type	Sample number	Platform
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
C   GSE35465	Chip-seq;RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
GSE199850	scRNA-seq	1	HiSeq X Ten (Homo sapiens)
C   GSE68402	Chip-seq	26	Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
C   GSE270130	Chip-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
E   C   GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
C   GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
E   GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• Expression profiling
• Genome binding/occupancy profiling

When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.

> Dataset: GSE100400 - NRXN3 expression across samples

Volcano Plot

Bar Plot

> Dataset: GSE94660 - NRXN3 expression across samples

Volcano Plot

Bar Plot