Gene Name	OTOG
Gene ID	340990
Gene Full Name	otogelin
Gene Alias	DFNB18B|MLEMP|OTGN
Transcripts	ENSG00000188162
Virus	HTLV1
Gene Type	protein-coding
HPA Location Info	Secreted in other tissues;
Membrane Info	Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	Q6ZRI0
HGNC ID	HGNC:8516
OMIM ID	604487
Summary	The protein encoded by this gene is a component of the acellular membranes of the inner ear. Disruption of the orthologous mouse gene shows that it plays a role in auditory and vestibular functions. It is involved in fibrillar network organization, the anchoring of otoconial membranes and cupulae to the neuroepithelia, and likely in sound stimulation resistance. Mutations in this gene cause autosomal recessive nonsyndromic deafness, type 18B. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6011590	chr11	23	0	3	26	View
6019903	chr11	4	1	2	7	View

Data ID	Experiment type	Sample number	Platform
GSE189602	Methylation profiling (Array)	4	Infinium MethylationEPIC
GSE168557	Expression array	6	Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
C   GSE94732	Chip-seq	24	Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE94732 - OTOG peak across samples

Peak Plot