HBV Target gene Detail Information

> PDE3A Gene Search Result


Gene Information
Gene Name PDE3A
Gene ID 5139
Gene Full Name phosphodiesterase 3A
Gene Alias CGI-PDE|CGI-PDE A|CGI-PDE-A|HTNB
Transcripts ENSG00000172572
Virus HBV
Gene Type protein-coding
HPA Location Info Plasma membrane;
Membrane Info Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins
Uniport_ID Q14432
HGNC ID HGNC:8778
OMIM ID 123805
Summary This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Target gene [PDE3A] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004759 chr12 52 16 2 70 View
1005273 chr12 17 5 35 57 View
1005544 chr12 17 3 32 52 View
1006791 chr12 21 12 1 34 View
1008637 chr12 18 1 1 20 View
1009318 chr12 13 3 0 16 View
1009338 chr12 13 3 0 16 View
1009347 chr12 13 3 0 16 View
1009351 chr12 13 3 0 16 View
1009379 chr12 13 3 0 16 View
1009393 chr12 13 3 0 16 View
1013253 chr12 1 4 0 5 View
1013908 chr12 3 1 0 4 View
1013972 chr12 3 1 0 4 View
1014006 chr12 3 1 0 4 View
1014019 chr12 3 1 0 4 View
1014082 chr12 3 1 0 4 View
1014100 chr12 3 1 0 4 View
1014109 chr12 3 1 0 4 View
1014122 chr12 3 1 0 4 View
1019789 chr12 0 0 0 0 View

Target gene [PDE3A] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
C
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
GSE94660 RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE35465 - PDE3A peak across samples

Peak Plot

> Dataset: GSE68402 - PDE3A peak across samples

Peak Plot

> Dataset: GSE270130 - PDE3A peak across samples

Peak Plot

> Dataset: GSE100400 - PDE3A peak across samples

Peak Plot

> Dataset: GSE131257 - PDE3A peak across samples

Peak Plot