Gene Information
|
Gene Name
|
PSMA6 |
|
Gene ID
|
5687
|
|
Gene Full Name
|
proteasome 20S subunit alpha 6 |
|
Gene Alias
|
IOTA|PROS27|p27K |
|
Transcripts
|
ENSG00000100902
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Nucleoplasm;Primary cilium, Primary cilium tip, Cytosol, Perinuclear theca, Calyx, Connecting piece, Flagellar centriole, Mid piece, End piece; 
|
|
Membrane Info
|
Enzymes, Human disease related genes, Plasma proteins, Predicted intracellular proteins |
|
Uniport_ID
|
P60900
|
|
HGNC ID
|
HGNC:9535
|
|
OMIM ID
|
602855 |
|
Summary
|
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013] |
Target gene [PSMA6] related to VISs 
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6001063 |
chr14 |
323 |
203 |
83 |
609 |
View |
| 6010862 |
chr14 |
7 |
18 |
4 |
29 |
View |
Target gene [PSMA6] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
GSE10789
|
Expression array |
6 |
NCI/ATC Hs-OperonV3 |
|
GSE224047
|
RNA-seq |
10 |
Illumina NextSeq 500 (Homo sapiens) |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - PSMA6 peak across samples
|
Peak Plot
|
|
|
HTLV1 Target gene Detail Information
