Gene Information
|
Gene Name
|
PTPRD |
|
Gene ID
|
5789
|
|
Gene Full Name
|
protein tyrosine phosphatase receptor type D |
|
Gene Alias
|
HPTP|HPTPD|HPTPDELTA|PTPD|R-PTP-delta|RPTPDELTA |
|
Transcripts
|
ENSG00000153707
|
|
Virus
|
HBV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Vesicles;Nucleoplasm;Intracellular and membrane;
|
|
Membrane Info
|
Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
P23468
|
|
HGNC ID
|
HGNC:9668
|
|
OMIM ID
|
601598 |
|
Summary
|
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010] |
Target gene [PTPRD] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1009677 |
chr9 |
6 |
5 |
4 |
15 |
View |
| 1009938 |
chr9 |
6 |
3 |
5 |
14 |
View |
| 1011026 |
chr9 |
6 |
1 |
3 |
10 |
View |
| 1013631 |
chr9 |
2 |
3 |
0 |
5 |
View |
| 1014288 |
chr9 |
2 |
0 |
2 |
4 |
View |
| 1015285 |
chr9 |
0 |
2 |
0 |
2 |
View |
| 1015404 |
chr9 |
0 |
2 |
0 |
2 |
View |
| 1015450 |
chr9 |
0 |
2 |
0 |
2 |
View |
| 1015500 |
chr9 |
0 |
2 |
0 |
2 |
View |
| 1017612 |
chr9 |
0 |
0 |
0 |
0 |
View |
| 1017618 |
chr9 |
0 |
0 |
0 |
0 |
View |
| 1018060 |
chr9 |
0 |
0 |
0 |
0 |
View |
| 1018111 |
chr9 |
0 |
0 |
0 |
0 |
View |
| 1018577 |
chr9 |
0 |
0 |
0 |
0 |
View |
| 1020289 |
chr9 |
15 |
9 |
11 |
35 |
View |
| 1020719 |
chr9 |
0 |
0 |
0 |
0 |
View |
| 1021112 |
chr9 |
1 |
0 |
0 |
1 |
View |
| 1021862 |
chr9 |
0 |
0 |
0 |
0 |
View |
| 1021863 |
chr9 |
0 |
2 |
0 |
2 |
View |
| 1024527 |
chr9 |
1 |
11 |
31 |
43 |
View |
| 1040785 |
chr9 |
0 |
0 |
0 |
0 |
View |
| 1043430 |
chr9 |
1 |
1 |
0 |
2 |
View |
| 1043431 |
chr9 |
1 |
0 |
0 |
1 |
View |
| 1043432 |
chr9 |
0 |
0 |
1 |
1 |
View |
| 1043433 |
chr9 |
1 |
0 |
0 |
1 |
View |
| 1043434 |
chr9 |
0 |
2 |
0 |
2 |
View |
Target gene [PTPRD] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE236281
|
RNA-seq |
12 |
Illumina MiSeq (Homo sapiens) |
|
C GSE35465
|
Chip-seq;RNA-seq |
6 |
Illumina HiSeq 2000 (Homo sapiens) |
|
GSE199850
|
scRNA-seq |
1 |
HiSeq X Ten (Homo sapiens) |
|
C GSE68402
|
Chip-seq |
26 |
Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens) |
|
TCGA_LIHC_HBV
|
DNA methylation sequencing;RNA-seq |
97 |
TCGA |
|
C GSE270130
|
Chip-seq |
27 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
GSE224901
|
RNA-seq |
21 |
Illumina NovaSeq 6000 (Homo sapiens) |
|
E C GSE100400
|
Chip-seq;RNA-seq;4C_cccDNA |
31 |
Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus) |
|
GSE173897
|
RNA-seq |
95 |
Illumina HiSeq 4000 (Homo sapiens) |
|
GSE262515
|
RNA-seq |
21 |
Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus) |
|
GSE110345
|
RNA-seq |
4 |
Illumina HiSeq 2500 (Homo sapiens) |
|
C GSE131257
|
ATAC-seq;RNA-seq |
19 |
Illumina HiSeq 2500 (Homo sapiens) |
|
GSE94660
|
RNA-seq |
42 |
Illumina HiSeq 2500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE100400 - PTPRD expression across samples
|
Volcano Plot
|
Bar Plot
|
|
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