Gene Information
|
Gene Name
|
RIGI |
|
Gene ID
|
23586
|
|
Gene Full Name
|
RNA sensor RIG-I |
|
Gene Alias
|
DDX58|RIG-I|RIG1|RLR-1|SGMRT2 |
|
Transcripts
|
ENSG00000107201
|
|
Virus
|
YFV |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Plasma membrane, Cytosol; 
|
|
Membrane Info
|
Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins |
|
Uniport_ID
|
O95786
|
|
HGNC ID
|
HGNC:19102
|
|
OMIM ID
|
609631 |
|
Summary
|
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2. [provided by RefSeq, Aug 2020] |
Target gene [RIGI] related to virus gene/protein/region 
Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section
| ID |
PMID |
Mutation |
Gene/Protein/Region |
Encoding Gene/Protein |
Disease |
Description |
Detail |
| 1 |
26187414 |
E218A |
NS5
|
NS5
|
Cell line
|
T
|
View |
Target gene [RIGI] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
E GSE99081
|
RNA-seq |
24 |
Illumina HiSeq 2500 (Homo sapiens) |
When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.
> Dataset: GSE99081 - RIGI expression across samples
|
Volcano Plot
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Bar Plot
|
|
|
YFV Target gene Detail Information
