Gene Name	RIMBP2
Gene ID	23504
Gene Full Name	RIMS binding protein 2
Gene Alias	PPP1R133|RBP2|RIM-BP2
Transcripts	ENSG00000060709
Virus	HBV
Gene Type	protein-coding
HPA Location Info	Nucleoplasm;Golgi apparatus, Cytosol;
Membrane Info	Predicted intracellular proteins
Uniport_ID	O15034
HGNC ID	HGNC:30339
OMIM ID	611602
Summary	Predicted to enable voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels and voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential. Predicted to be a structural constituent of presynaptic active zone. Predicted to be involved in neuromuscular synaptic transmission; regulation of calcium-dependent activation of synaptic vesicle fusion; and regulation of presynaptic membrane potential. Predicted to be located in plasma membrane and synapse. Predicted to be active in calyx of Held; glutamatergic synapse; and presynaptic active zone cytoplasmic component. [provided by Alliance of Genome Resources, Apr 2025]

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1011471	chr12	9	0	0	9	View
1011640	chr12	7	1	0	8	View
1013845	chr12	2	2	0	4	View
1021110	chr12	7	1	0	8	View

Data ID	Experiment type	Sample number	Platform
GSE236281	RNA-seq	12	Illumina MiSeq (Homo sapiens)
C   GSE35465	Chip-seq;RNA-seq	6	Illumina HiSeq 2000 (Homo sapiens)
C   GSE68402	Chip-seq	26	Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV	DNA methylation sequencing;RNA-seq	97	TCGA
C   GSE270130	Chip-seq	27	Illumina NovaSeq 6000 (Homo sapiens)
GSE224901	RNA-seq	21	Illumina NovaSeq 6000 (Homo sapiens)
C   GSE100400	Chip-seq;RNA-seq;4C_cccDNA	31	Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897	RNA-seq	95	Illumina HiSeq 4000 (Homo sapiens)
GSE262515	RNA-seq	21	Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345	RNA-seq	4	Illumina HiSeq 2500 (Homo sapiens)
C   GSE131257	ATAC-seq;RNA-seq	19	Illumina HiSeq 2500 (Homo sapiens)
GSE94660	RNA-seq	42	Illumina HiSeq 2500 (Homo sapiens)

• Genome binding/occupancy profiling

When the gene can detect a peak in the dataset, a peak plot will be displayed.

> Dataset: GSE35465 - RIMBP2 peak across samples

Peak Plot

> Dataset: GSE68402 - RIMBP2 peak across samples

Peak Plot

> Dataset: GSE270130 - RIMBP2 peak across samples

Peak Plot

> Dataset: GSE100400 - RIMBP2 peak across samples

Peak Plot

> Dataset: GSE131257 - RIMBP2 peak across samples

Peak Plot