HBV Target gene Detail Information

> ROBO2 Gene Search Result


Gene Information
Gene Name ROBO2
Gene ID 6092
Gene Full Name roundabout guidance receptor 2
Gene Alias SAX3
Transcripts ENSG00000185008
Virus HBV
Gene Type protein-coding
HPA Location Info Vesicles, Plasma membrane;
Membrane Info Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9HCK4
HGNC ID HGNC:10250
OMIM ID 602431
Summary The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Target gene [ROBO2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004640 chr3 64 9 0 73 View
1007029 chr3 18 9 4 31 View
1007030 chr3 19 8 4 31 View
1012707 chr3 5 1 0 6 View
1013952 chr3 2 1 1 4 View
1014718 chr3 1 1 1 3 View
1017616 chr3 0 0 0 0 View
1021173 chr3 0 0 0 0 View
1042771 chr3 0 0 0 0 View

Target gene [ROBO2] related to Omics data
Data ID Experiment type Sample number Platform
GSE236281 RNA-seq 12 Illumina MiSeq (Homo sapiens)
C
  GSE35465 		Chip-seq;RNA-seq 6 Illumina HiSeq 2000 (Homo sapiens)
GSE199850 scRNA-seq 1 HiSeq X Ten (Homo sapiens)
C
  GSE68402 		Chip-seq 26 Illumina MiSeq (Homo sapiens);Illumina HiSeq 2500 (Homo sapiens)
TCGA_LIHC_HBV DNA methylation sequencing;RNA-seq 97 TCGA
C
  GSE270130 		Chip-seq 27 Illumina NovaSeq 6000 (Homo sapiens)
GSE224901 RNA-seq 21 Illumina NovaSeq 6000 (Homo sapiens)
E
 
C
  GSE100400 		Chip-seq;RNA-seq;4C_cccDNA 31 Illumina NextSeq 500 (Homo sapiens);Illumina NextSeq 500 (Mus musculus)
GSE173897 RNA-seq 95 Illumina HiSeq 4000 (Homo sapiens)
GSE262515 RNA-seq 21 Illumina HiSeq 2500 (Homo sapiens);Illumina HiSeq 2500 (Mus musculus)
GSE110345 RNA-seq 4 Illumina HiSeq 2500 (Homo sapiens)
C
  GSE131257 		ATAC-seq;RNA-seq 19 Illumina HiSeq 2500 (Homo sapiens)
E
  GSE94660 		RNA-seq 42 Illumina HiSeq 2500 (Homo sapiens)


When the query gene is differentially changed in the dataset, a volcano/bar plot will be displayed.


> Dataset: GSE100400 - ROBO2 expression across samples

Volcano Plot

Bar Plot

> Dataset: GSE94660 - ROBO2 expression across samples

Volcano Plot

Bar Plot