Gene Information
|
Gene Name
|
ROBO2 |
|
Gene ID
|
6092
|
|
Gene Full Name
|
roundabout guidance receptor 2 |
|
Gene Alias
|
SAX3 |
|
Transcripts
|
ENSG00000185008
|
|
Virus
|
HTLV1 |
|
Gene Type
|
protein-coding |
|
HPA Location Info
|
Vesicles, Plasma membrane;
|
|
Membrane Info
|
Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
Q9HCK4
|
|
HGNC ID
|
HGNC:10250
|
|
OMIM ID
|
602431 |
|
Summary
|
The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014] |
Target gene [ROBO2] related to VISs
Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 6005792 |
chr3 |
3 |
22 |
55 |
80 |
View |
| 6005857 |
chr3 |
16 |
45 |
18 |
79 |
View |
| 6010530 |
chr3 |
27 |
3 |
0 |
30 |
View |
| 6016443 |
chr3 |
10 |
1 |
1 |
12 |
View |
| 6016991 |
chr3 |
4 |
5 |
2 |
11 |
View |
| 6017761 |
chr3 |
10 |
0 |
0 |
10 |
View |
| 6018118 |
chr3 |
6 |
0 |
2 |
8 |
View |
| 6019274 |
chr3 |
4 |
1 |
3 |
8 |
View |
| 6019421 |
chr3 |
4 |
0 |
4 |
8 |
View |
| 6019595 |
chr3 |
6 |
0 |
2 |
8 |
View |
| 6019709 |
chr3 |
5 |
2 |
0 |
7 |
View |
| 6022490 |
chr3 |
1 |
3 |
1 |
5 |
View |
| 6024520 |
chr3 |
0 |
3 |
0 |
3 |
View |
| 6026470 |
chr3 |
0 |
2 |
0 |
2 |
View |
| 6026967 |
chr3 |
0 |
2 |
0 |
2 |
View |
| 6027285 |
chr3 |
2 |
0 |
0 |
2 |
View |
| 6028100 |
chr3 |
0 |
0 |
1 |
1 |
View |
| 6028562 |
chr3 |
0 |
1 |
0 |
1 |
View |
| 6029110 |
chr3 |
1 |
0 |
0 |
1 |
View |
| 6029300 |
chr3 |
0 |
1 |
0 |
1 |
View |
| 6029301 |
chr3 |
1 |
0 |
0 |
1 |
View |
| 6029302 |
chr3 |
1 |
0 |
0 |
1 |
View |
| 6030559 |
chr3 |
0 |
0 |
0 |
0 |
View |
| 6030787 |
chr3 |
0 |
0 |
0 |
0 |
View |
| 6030943 |
chr3 |
0 |
0 |
0 |
0 |
View |
| 6031282 |
chr3 |
0 |
0 |
0 |
0 |
View |
| 6031554 |
chr3 |
0 |
0 |
0 |
0 |
View |
| 6031579 |
chr3 |
0 |
0 |
0 |
0 |
View |
| 6033076 |
chr3 |
0 |
0 |
0 |
0 |
View |
| 6033279 |
chr3 |
0 |
0 |
0 |
0 |
View |
| 6033339 |
chr3 |
0 |
0 |
0 |
0 |
View |
| 6033376 |
chr3 |
0 |
0 |
0 |
0 |
View |
Target gene [ROBO2] related to Omics data
| Data ID |
Experiment type |
Sample number |
Platform |
|
GSE189602
|
Methylation profiling (Array) |
4 |
Infinium MethylationEPIC |
|
GSE168557
|
Expression array |
6 |
Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version) |
|
C GSE94732
|
Chip-seq |
24 |
Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens) |
|
GSE136189
|
Methylation profiling (Array) |
40 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip |
When the gene can detect a peak in the dataset, a peak plot will be displayed.
> Dataset: GSE94732 - ROBO2 peak across samples
|
Peak Plot
|
|
|