HTLV1 Target gene Detail Information

> ROBO2 Gene Search Result


Gene Information
Gene Name ROBO2
Gene ID 6092
Gene Full Name roundabout guidance receptor 2
Gene Alias SAX3
Transcripts ENSG00000185008
Virus HTLV1
Gene Type protein-coding
HPA Location Info Vesicles, Plasma membrane;
Membrane Info Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q9HCK4
HGNC ID HGNC:10250
OMIM ID 602431
Summary The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Target gene [ROBO2] related to VISs

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in this section


DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6005792 chr3 3 22 55 80 View
6005857 chr3 16 45 18 79 View
6010530 chr3 27 3 0 30 View
6016443 chr3 10 1 1 12 View
6016991 chr3 4 5 2 11 View
6017761 chr3 10 0 0 10 View
6018118 chr3 6 0 2 8 View
6019274 chr3 4 1 3 8 View
6019421 chr3 4 0 4 8 View
6019595 chr3 6 0 2 8 View
6019709 chr3 5 2 0 7 View
6022490 chr3 1 3 1 5 View
6024520 chr3 0 3 0 3 View
6026470 chr3 0 2 0 2 View
6026967 chr3 0 2 0 2 View
6027285 chr3 2 0 0 2 View
6028100 chr3 0 0 1 1 View
6028562 chr3 0 1 0 1 View
6029110 chr3 1 0 0 1 View
6029300 chr3 0 1 0 1 View
6029301 chr3 1 0 0 1 View
6029302 chr3 1 0 0 1 View
6030559 chr3 0 0 0 0 View
6030787 chr3 0 0 0 0 View
6030943 chr3 0 0 0 0 View
6031282 chr3 0 0 0 0 View
6031554 chr3 0 0 0 0 View
6031579 chr3 0 0 0 0 View
6033076 chr3 0 0 0 0 View
6033279 chr3 0 0 0 0 View
6033339 chr3 0 0 0 0 View
6033376 chr3 0 0 0 0 View

Target gene [ROBO2] related to Omics data
Data ID Experiment type Sample number Platform
GSE189602 Methylation profiling (Array) 4 Infinium MethylationEPIC
GSE168557 Expression array 6 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Feature Number version)
C
  GSE94732
Chip-seq 24 Illumina NextSeq 500 (Homo sapiens);illumina Genome Analyzer IIx (Homo sapiens)
GSE136189 Methylation profiling (Array) 40 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482);Illumina Infinium HumanMethylation850 BeadChip


When the gene can detect a peak in the dataset, a peak plot will be displayed.


> Dataset: GSE94732 - ROBO2 peak across samples

Peak Plot