Gene Name	SPCS1
Gene ID	28972
Gene Full Name	signal peptidase complex subunit 1
Gene Alias	HSPC033|SPC1|SPC12|YJR010C-A
Transcripts	ENSG00000114902
Virus	JEV
Gene Type	protein-coding
HPA Location Info	Golgi apparatus, Vesicles;
Membrane Info	Metabolic proteins, Predicted membrane proteins
Uniport_ID	Q9Y6A9
HGNC ID	HGNC:23401
OMIM ID	610358
Summary	Predicted to enable ribosome binding activity. Involved in signal peptide processing; viral protein processing; and virion assembly. Located in endoplasmic reticulum membrane. Part of signal peptidase complex. [provided by Alliance of Genome Resources, Apr 2025]

Mutation Table: if previous studies reported that target gene was related to virus gene/region/protein, the information in this literature was listed in this section

ID	PMID	Mutation	Gene/Protein/Region	Encoding Gene/Protein	Disease	Description	Detail
1	29593046	G12A	NS2B	NS2B	Cell line	R T	View
2	29593046	G37A	NS2B	NS2B	Cell line	R T	View
3	29593046	G47A	NS2B	NS2B	Cell line	R T	View
4	29593046	P112A	NS2B	NS2B	Cell line	R T	View

Data ID	Experiment type	Sample number	Platform
GSE221680	RNA-seq	6	Illumina HiSeq 2500 (Homo sapiens)